Signs and symptoms of bone sarcomas
Persistent bone pain — especially at night — swelling near a joint, or a fracture from minor trauma. Key red flags every patient and parent should know.
Written by Dr Srimanth B S · Last reviewed: 21 October 2026
Primary bone cancers are rare but treatable. Modern multimodal care combining chemotherapy, surgery and reconstruction has transformed survival and limb-preservation rates. Explore the major subtypes below and watch short explainers on symptoms, tests and risk factors.
Most common primary bone cancer in children and young adults — typically around the knee or shoulder.
Aggressive small round-cell tumour of bone affecting children and adolescents.
Cartilage-forming malignant tumour, more common in middle and older age groups.
Rare low-grade malignant tumour, classically of the tibial diaphysis.
Rare entities — chordoma, undifferentiated pleomorphic sarcoma of bone, leiomyosarcoma of bone and more.
Quick, patient-friendly explainers on the signs, tests and risk factors for primary bone cancers.
Persistent bone pain — especially at night — swelling near a joint, or a fracture from minor trauma. Key red flags every patient and parent should know.
X-ray, MRI, CT chest, whole-body PET-CT and image-guided core needle biopsy — the sequence that confirms diagnosis and stages the disease.
Multimodal care combining chemotherapy, surgery (limb salvage where possible) and — for selected tumours — radiotherapy, delivered by a specialist team.